Dicky John Davis G

Dicky John Davis G

Associate Professor, Department of Bioinformatics

Sri Ramachandra Institute of Higher Education & Research, Chennai

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Employment

Associate Professor, Department of Bioinformatics

Sri Ramachandra Institute of Higher Education & Research (DU), Chennai

September 2023 - Present

Assistant Professor, Department of Bioinformatics

Sri Ramachandra Institute of Higher Education & Research (DU), Chennai

October 2014 - August 2023

Lecturer, Department of Bioinformatics

Sri Ramachandra University, Chennai

July 2004 - September 2014

Lecturer, Department of Biotechnology

Kumararani Meena Muthiah College of Arts & Science, Chennai

August 2002 - June 2004

Manager R&D

Nichi-In Drugs & Devices Pvt. Ltd., Chennai

November 2001 - February 2002

Territory Manager

DSS Imagetech Pvt. Ltd., Chennai

September 1998 - October 2001

Education

Ph.D. Bioinformatics

Sri Ramachandra University, 2014

M.Phil. Biotechnology

Bharathidasan University, 2005

P.G. Diploma in Bioinformatics

Small Industries Service Institute, 2003

M.Sc. Molecular Biology

University of Madras, 1998

P.G. Diploma in Advanced Medical Laboratory Technology

Tamilnad Hospital, 1996

B.Sc. Microbiology

University of Madras, 1994

Awards & Honors

Awarded for Meritorious Research Publication, Sri Ramachandra University, 2015

Awarded for Meritorious Research Publication, Sri Ramachandra University, 2012

Qualified Joint CSIR UGC National Eligibility Test (NET) for Lectureship, June 2011

Research Projects

In silico studies with different Unani formulations

Regional Research Institute of Unani Medicine (RRIUM), Chennai, July 2020 (1 year), ₹1.5 Lakhs

Nuclear factor-κB inhibition in human urothelial carcinoma by a bioactive peptide using in-vitro and in-silico studies

Young Faculty Grant, Sri Ramachandra University, November 2014 (1 year), ₹1 Lakh

Chemoinformatics database of marine algae

Department of Bioinformatics, Sri Ramachandra University, June 2009 (5 years), ₹1.25 Lakhs

Journal Publications (28)

Anti-lipidemic and anti-diabetic properties of Gymnema sylvestre saponins: an in-silico approach

R. Archana Preetha, G. Dicky John Davis*, M. Gowri Neelima, B.S. Chaitra, B. Kirankumar.

In Silico Pharmacology, Volume 13, June 2025, Article 94.

PMID: 40552354 | PMCID: PMC12182551 |In Silico Pharmacol | PDF

Decoding the Triterpenoid Gymnemic Acid Biosynthetic Pathway in Gymnema sylvestre

Archana Preetha R, Dicky John Davis G*, Gowri Neelima M, Chaitra B S, Kirankumar B.

Journal of Neonatal Surgery, Volume 14, Issue 7S, March 2025, Pages 464–470.

J Neonatal Surg | PDF

Identification and Validation of B-Cell Epitopes on the VP1 Protein of Parvovirus B19 through Molecular Docking and Dynamics Simulation

Reuben Kuruvilla Thomas, Ambritha Balasundaram, Gracy Fathima, Sathish Sankar, Dicky John Davis G*, Mageshbabu Ramamoorthy, Nithiyanandan Saravanan, Swati Kumari, Sudhabharathi Reju, Ramya Barani, Sribal Selvarajan, Krishnasamy Kaveri, John Fletcher, Jason T. Blackard, George Priya Doss C, Padma Srikanth.

ACS Omega, Volume 10, Issue 4, January 2025, Pages 3598–3609.

PMID: 39926541 | PMCID: PMC11799995 | ACS Omega | PDF

Molecular docking and MD simulation approach to identify potential phytochemical lead molecule against triple negative breast cancer

Pranaya Sankaranarayanan, Dicky John Davis G*, Abhinand PA, M Manikandan, Arabinda Ghosh.

F1000Research, Volume 13, October 2024, 1271.

PMID: 40860264 | PMCID: PMC12375911 | F1000Res | PDF

In silico preliminary evaluation of bioactive compounds from five Unani drugs as potential SARS-CoV-2 inhibitors

Noman Anwar, G. Dicky John Davis, Syed Ibrahim, Meena R P, Zeba Afnaan, N. Zaheer Ahmed.

Indian Journal of Traditional Knowledge, Volume 23, Issue 3, March 2024, Pages 247-261.

IJTK | PDF

Antifibrotic effect of silymarin on arecoline-induced fibrosis in primary human buccal fibroblasts: an in silico and in vitro analysis

Divyambika Catakapatri Venugopal, Paramesh Viswanathan, Soundharya Ravindran, Alan Mathew Punnoose, Madhavan Yasasve, Davis G. Dicky John, Lavanya Prabhakar, Gnanasambandan Ramanathan, Sathasivasubramanian Sankarapandian, Vijayalakshmi Ramshankar.

Molecular Biology Reports, Volume 51, Issue 3, February 2024, Article 303.

PMID: 38356030 | Mol Biol Rep | PDF

Computational analysis of marine algal compounds for obesity management against pancreatic lipase

Lavanya Prabhakar, Davis G. Dicky John*, Satya Ranjan Singh, Ayaluru Murali.

Journal of Biomolecular Structure and Dynamics, Volume 41, Issue 11, July 2023, Pages 4863-4872.

PMID: 35575483 | J Biomol Struct Dyn | PDF

Chemo-structural diversity of anti-obesity compound database

Lavanya Prabhakar, Dicky John Davis G*.

Journal of Molecular Graphics and Modelling, Volume 120, May 2023, Article 108414.

PMID: 36702059 | J Mol Graph Model | PDF

Meta-analysis of lean and obese RNA-seq datasets to identify genes targeting obesity

Lavanya Prabhakar, Dicky John Davis G*.

Bioinformation, Volume 19, Issue 3, March 2023, Pages 331-335.

PMID: 37808366 | PMCID: PMC10557442 | Bioinformation | PDF

Computational study of potential inhibitors for fat mass and obesity-associated protein from seaweed and plant compounds

Lavanya Prabhakar, Dicky John Davis G*.

PeerJ, October 2022, 10:e14256.

PMID: 36299509 | PMCID: PMC9590420 | PeerJ | PDF

Comparative Study of three Clustering Algorithms for Microarray Data

Noveenaa Pious, G. Dicky John Davis*.

Global Journal of Science Frontier Research: G, Volume 22, Issue 1, 2022, Pages 11-17.

GJSFR-G | PDF

Benefits of merging paired-end reads before pre-processing environmental metagenomics data

Midhuna Immaculate Joseph Maran, Dicky John Davis G*.

Marine Genomics, Volume 61, February 2022, Pages 100914.

PMID: 34864203 | Mar Genomics | PDF

Arq Ajīb – a wonder Unani formulation for inhibiting SARS-CoV-2 spike glycoprotein and mainPV protease – an insilico approach

N Zaheer Ahmed, Dicky John Davis G, Asim Ali Khan, Lavanya Prabhakar, Meena Ram Paratap, Zeba Afnaan, Meera Devi Sri, Noman Anwar.

Journal of Complementary and Integrative Medicine, Volume 20, Issue 3, October 2021, Pages 637-649.

PMID: 34679263 | J Complement Integr Med | PDF

Antimicrobial, HPTLC and in-silico studies of Habb-e-Bukhar widely used in Unani system of Medicine

Asim Ali Khan, Rampratap Meena, Meera Devi Sri P, G. Dicky John Davis, Zaheer Ahmed N, Mageswari S, Jaculin Raiza A, Sadaf Subhani, Selvarani R.

International Journal of Recent Scientific Research, Volume 12, Issue 8, August 2021, Pages 42788-42793.

IJRSR | PDF

In-Silico Evaluation of Tiryaq-E-Wabai, an Unani Formulation for its Potency against SARS-CoV-2 Spike Glycoprotein and Main Protease

N. Zaheer Ahmed, G. Dicky John Davis, Noman Anwar, Asim Ali Khan, Ram Pratap Meena, Zeba Afnaan, Meera Devi Sri.

Journal of Drug Delivery & Therapeutics, Volume 11, Issue 4, 15 August 2021, Pages 86-100.

JDDT | PDF

Bladder neoplasms and NF-κB: an unfathomed association

Charles Emmanuel Jebaraj Walter, Sankari Durairajan, Kalaiselvi Periyandavan, George Priya Doss C, Dicky John Davis G, Hannah Rachel Vasanthi A, Thanka Johnson, Hatem Zayed.

Expert Review of Molecular Diagnostics, Volume 20, Issue 5, May 2020, Pages 497-508.

PMID: 32228251 | Expert Rev Mol Diagn | PDF

Selective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD Peptide

Sankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan, George Priya Doss C, Dicky John Davis G, Hannah Rachel Vasanthi A, Gayathri Thiruvengadam, Thanka Johnson.

American Journal of Biochemistry and Biotechnology, Volume 16, Issue 2, April 2020, Pages 184-198.

Am J Biochem Biotechnol | PDF

GenPop - An Online Tool to Analyze Human Population Genetic Data

B. Arundhati Mahesh, E. Kannan, G. Dicky John Davis, PK Ragunath.

Bioinformation, Volume 16, Issue 2, February 2020, Pages 149-152.

PMID: 32405166 | PMCID: PMC7196168 | Bioinformation | PDF

Breast Cancer Susceptibility Gene in Base Excision Repair Pathway in a Southern Indian Population

Andrea Mary Francis, R. Ramya, Nalini Ganesan, Solomon F. D. Paul, AK. Munirajan, P. Kumarasamy, G. Dicky John Davis.

Journal of Clinical & Diagnostic Research, Volume 12 Issue 9, September 2018, Pages 1-6.

J Clin Diagn Res | PDF

Differential expression of NF-κB heterodimer RelA/p50 in human urothelial carcinoma

Sankari Durairajan, Charles Emmanuel Jebaraj Walter, Mary Divya Samuel, Dinesh Palani, G. Dicky John Davis, C. George Priya Doss, Sneha Pasupati, Thanka Johnson.

PeerJ, September 2018, 6:e5563.

PMID: 30225173 | PMCID: PMC6139250 | PeerJ | PDF

Motif Finding Tool Using Perl CGI

Arundhati Mahesh, G. Dicky John Davis, PK. Ragunath, E. Kannan.

International Journal of Advanced Research in Engineering and Technology, Volume 9, Issue 4, July 2018, Pages 1–5.

IJARET | PDF

Mobile App for Cardiac risks

S. Mariya Thangam, G. Dicky John Davis, B. Bagya Sreedharaman, Arundhati Mahesh.

International Journal of Computer Engineering & Technology, Volume 9, Issue 3, July 2018, Pages 218–221.

IJCET | PDF

QSAR based docking studies of marine algal anticancer compounds as inhibitors of protein kinase B (PKBβ)

G. Dicky John Davis*, A. Hannah Rachel Vasanthi.

European Journal of Pharmaceutical Sciences, Volume 76, August 2015, Pages 110–118.

PMID: 25936945 | Eur J Pharm Sci | PDF

Glucose oxidase incorporated collagen matrices for dermal wound repair in diabetic rat models: a biochemical study

V. Arul, J. Gunasingh Masilamoni, E. Philip Jesudason, P. J. Jaji, M. Inayathullah, G. Dicky John Davis, S. Vignesh, R. Jayakumar.

Journal of Biomaterials Applications, Volume 26, Issue 8, May 2012, Pages 917-938.

PMID: 21363874 | J Biomater Appl | PDF

Seaweed metabolite database (SWMD): A database of natural compounds from marine algae

G. Dicky John Davis*, A. Hannah Rachel Vasanthi.

Bioinformation, Volume 5, Issue 8, January 2011, Pages 361-364.

PMID: 21423723 | PMCID: PMC3053594 | Bioinformation | PDF

Radioprotective effect of DL-α-lipoic acid on mice skin fibroblasts

G. Dicky John Davis*, J. Gunasingh Masilamoni, V. Arul, M. Siva Muthu Kumar, U. Baraneedharan, Solomon F. D. Paul, I. Vignesh Sakthivelu, E. Philip Jesudason, R. Jayakumar.

Cell Biology and Toxicology, Volume 25, Issue 4, August 2009, Pages 331-340.

PMID: 18553143 | Cell Biol Toxicol | PDF

Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism

J. Gunasingh Masilamoni, E. Philip Jesudason, Ben S. Ashok, R. Kirubagaran, W. Charles E. Jebaraj, G. Dicky John Davis, S. Vignesh, S. Dhandayuthapani, R. Jayakumar.

Life Sciences, Volume 83, Issues 3-4, 18 July 2008, Pages 96-102.

PMID: 18590917 | Life Sci | PDF

The protective role of dl-α-lipoic acid in biogenic amines catabolism triggered by Aβ amyloid vaccination in mice

E. Philip Jesudason, J. Gunasingh Masilamoni, R. Kirubagaran, G. Dicky John Davis, R. Jayakumar.

Brain Research Bulletin, Volume 65, Issue 4, 30 April 2005, Pages 361-367.

PMID: 15811602 | Brain Res Bull | PDF

Book Chapter Publications (2)

Chapter 1. Online Drug Data Banks and Molecular Libraries

G. Dicky John Davis*, R. Archana Preetha, M. Gowri Neelima.

Recent Advances in Computer Aided Drug Designing, Nova Publishers, 26 July 2021, Pages 1-9.

Nova Publishers | PDF

Clues for cancer from ocean-derived molecules and role of in silico techniques in anticancer drug discovery

G. Dicky John Davis, Veeresh Kumar Sali, Hannah R. Vasanthi.

Marine Pharmacognosy: Trends and Applications, CRC Press, December 2012, Pages 393-408.

CRC Press | PDF

Ph.D. Research

Cataloged the chemical compounds in marine algae by text- and data-mining published literature and hosted it in a public domain www.swmd.co.in. Cytotoxic compounds were subjected to QSAR analysis and potential inhibitor for Protein kinase B was predicted by docking studies from red algae. [2007 – 2014]

Title of the Thesis: “Anticancer potential of Marine Algae - a Chemoinformatics approach”

PDF

Invited Lectures (24)

Machine Learning-Guided Discovery of Anticancer Compounds

International CME on Genomics and Precision Medicine in Cancer, 1st February, 2025.

Organized by Faculty Of Clinical Research, Sri Ramachandra Institute of Higher Education and Research, Chennai - 600116.

Protein Structure Visualization and Molecular Docking

Workshop on Techniques in Computational Biology and its Applications, 10th January, 2024.

Organized by Department of Biotechnology, Hindustan Institute of Technology & Science, Chennai - 603103.

Computational Methods for Protein Structure Prediction

Workshop on In-Silico Drug Design and Development, 8th December, 2021.

Organized by Department of Chemical Engineering and Biotechnology, Hindustan Institute of Technology & Science, Chennai - 603103.

Molecular Modelling in Drug Discovery

Second National Workshop on Medical Bioinformatics, 19th March, 2020.

Organized by Department of Bioinformatics, Sri Ramachandra Institute of Higher Education and Research, Chennai - 600116.

Protein Structure analysis and Molecular Modeling

Workshop on Genomic and Proteomic analysis for improvement of Productivity in Farm Animal, 27 September 2019.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Insilico Drug Discovery

Application of Bioinformatics for Post Graduate Research, 10 August 2019.

Organized by Veterinary College and Research Institute, Namakkal - 637002.

Molecular Docking using Autodock Vina

Workshop on Vetinformatics, 6 March 2019.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Biotechnology in Medicine

Workshop on MOL BIO GIZMO, 31st January, 2019.

Organized by Department of Biotechnology, Kumararani Meena Muthiah College of Arts and Science, Adyar, Chennai - 600020.

Chemoinformatics and Marine Algal Drug Discovery

National Conference on Applications of Computational Biology in Omics, (ACBO-18), 11 October 2018.

Organized by Department of Biotechnology, Sri Sankara Arts and Science College, Enathur, Kanchipuram - 631561.

Protein Structure Analysis & Prediction

Workshop on Genomic and Proteomic Analysis for Improvement of Productivity in farm Animals, 9 August 2018.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Molecular Structure Analysis in Drug Designing

Workshop on In Silico Molecular Modeling and Drug Designing, 10 January 2018.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Protein sequence analysis, Molecular Modelling and docking studies

Workshop on Genomic and Proteomic analysis for improvement of productivity in farm animals, 13 July 2017.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Introduction to Proteomics and Protein sequence databanks, Molecular Modelling and Novel drug discovery

Workshop on Application of Bioinformatics in Animal Sciences, 29 May 2017.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

New Horizons of Bioinformatics in the Precision Medicine Era

Ascozyme - National Level Students Technical Symposium, 25 March 2017.

Organized by Department of Biotechnology, Shri Andal Alagar College of Engineering, Mamandur - 603111.

Significance of Structure Analysis in Computer Aided Drug Designing

Workshop on Computer Aided Drug Designing, 14 February 2017.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Protein structure visualization and prediction with bioinformatics tools

Workshop on Application of Bioinformatics in Proteome analysis, 22 September 2016.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Application of Bioinformatics in Phylogenetic Data Analysis

Workshop on Application of Bioinformatics in Genome analysis, 9 August 2016.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Significance of Phylogenetic analysis

Workshop on Recent Advancements in Comparative Genomics & Proteomics, 24 February 2016.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Novel drug discovery using a free software – Autodock

Workshop on Insilico drug designing & Development, 8 October 2015.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Recent advances & applications of PCR

State level workshop on PCR – a tool for molecular approach, 23 September 2015.

Organized by Department of Biotechnology, Kumararani Meena Muthiah College of Arts & Science, Adyar, Chennai - 600020.

An insight into drug targets and bioactive principles

Training Programme on Application of Bioinformatics in Veterinary Research, 8 July 2015.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Protein Modelling - Structure Prediction and Analysis

National workshop on Applications of Bioinformatics in Drug Designing, 25 September 2014.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Protein structure analysis

National workshop on Bioinformatics - a practical approach to genomics & proteomics, 8 October 2013.

Organized by Bioinformatics Centre & ARIS Cell, Madras Veterinary College, Chennai - 600007.

Cheminformatics database of red algae Laurencia Spp. for drug discovery

Second National Conference on Bioprospecting of Marine Resources with Special Reference to Marine Natural Products and Drug Discovery, 25-27 August 2010.

Organized by School of Marine Sciences, Department of Oceanography and Coastal Area Studies, Alagappa University, Karaikudi - 630003.

Contact

No. 137, Second Main Road, Ashtalakshmi Nagar, Alapakkam, Chennai, Tamil Nadu – 600 116, India.

Email: dicky@sriramachandra.edu.in, dickyjohn@sret.edu.in, dicky@swmd.co.in

Phone: (91) 8939278665

www.swmd.co.in